Organic Chemistry II Laboratory - CHM 246 at Piedmont Virginia Community College
https://courses.vccs.edu/colleges/pvcc/courses/CHM246-OrganicChemistryIILaboratory
Effective: 2020-05-01
Course Description
Introduces various methods and procedures used in present day organic laboratories. Covers the general techniques, organic synthesis, and the use of common spectroscopic instrumentation; synthesizing a variety of compounds; and analyzing the products through physical properties and spectroscopy. Part II of II.
Lecture 1 hour. Laboratory 3 hours. Total 4 hours per week.
2 credits
The course outline below was developed as part of a statewide standardization process.
General Course Purpose
Explores the physical properties and reactivity of organic compounds including common methods of separation, purification, and instrumental analysis. (Continued from CHM 245)
Course Prerequisites/Corequisites
Prerequisite: CHM 245; Corequisite: CHM 242.
Course Objectives
- Continued: Safety in the Organic Laboratory
- Use proper procedures and regulations for safe handling and use of chemicals in the organic chemistry laboratory
- Continued: Lab notebook
- Maintain a lab notebook and demonstrate proper recording, organization, and interpretation of scientific data
- Application of Laboratory techniques from CHM 245
- Formulate and perform the laboratory synthesis, purification, and characterization of the organic compounds studied; applying techniques covered in CHM 245.
- 1H and 13C NMR Spectroscopy
- Interpret spectra and identify compounds
- Synthesis and analysis
- Preparation and analysis of a variety of organic compounds.
- Perform theoretical yield, percent yield, and percent recovery calculations
- Potential reactions to be studied include: Grignard reaction, EAS reaction, Fischer esterification, aldol condensation, polymers
- Additional lab experiments that could be included: Synthesis of biodiesel,
- Diels-Alder, oxidation/reduction reactions, free radical halogenation, synthesis of aspirin, hydroboration-oxidation of alkenes
- Mechanism
- Propose mechanisms for all reactions.
- Theoretical understanding
- Explain the theoretical basis of all techniques and state reasons for use of specific reagents.
Major Topics to be Included
- Continued: Safety in the Organic Laboratory
- Continued: Lab notebook
- Application of Laboratory techniques from CHM 245
- 1N and 13C NMR Spectroscopy
- Mechanism
- Theoretical understanding